Interior of the Clay St. office
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Primary Care Doctor's Office in San Francisco, CA Financial District - Clay

Our beautiful and calming Financial District – Clay office offers exceptional primary care for adults of all ages, including seniors on Medicare. We’ve designed our member experience for real life — from same-day appointments that start on time to 24/7 video chat to compassionate providers who listen. We focus on building real relationships with patients and using technology to simplify every aspect of getting care. And we’re not just here for when you’re sick or injured. We can also help you meet physical and mental health goals, manage chronic illnesses, and live a happier, healthier life. Think of us as your home for healthcare

Join One Medical

Interested in becoming a member or learning more about One Medical?

Membership benefits you’ll enjoy

  • Get 24/7 on-demand care nationwide via Video Chat or Treat Me Now at no extra cost
  • Send and receive secure messages with a provider
  • Easily access your health records and care plans
  • Request prescription refills and renewals
  • Book an in-person or remote visit in a state where we have offices

559 Clay Street

1st Floor

San Francisco , CA 94111

Get Directions

Contact us:

Office Hours:

Mon, Tue, Thu: 8AM–6PM
Wed: 8AM–4:30PM
Fri: 8AM–5PM
Sat–Sun: Closed

Special Hours (Office and Lab):
06/19 Wed Closed

Lab Hours:

Mon–Wed: 8AM–12PM, 1PM–4PM
Thu–Fri: 8AM–5PM
Sat–Sun: Closed


Location details

Our Financial District doctor's office on Clay Street is across the street from the Transamerica Pyramid and next to Starbucks.


There is a parking garage at 475 Sansome with the entrance on Clay; the garage is not affiliated with One Medical or our building and we cannot validate parking. Metered street parking is available, but is limited. Please note, finding parking in the Financial District can be challenging, so please give yourself extra time if you're driving.

Our services

Think of us as your home for healthcare — your go-to for preventive care like physicals and screenings and your first stop when something feels off.

Frequently asked questions