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Downtown San Diego

Our Downtown San Diego office is located in the heart of the city, near Little Italy, the Gaslamp District, Broadway Pier, and Seaport Village.

Our whole patient experience is designed for real life — from same-day appointments that actually start on time to 24/7 video visits to compassionate providers who listen. We focus on building real relationships with patients and using technology to simplify every aspect of getting care. And we’re not just here for when you’re sick or injured. We can also help you meet physical and mental health goals, manage chronic illnesses, and live a happier, healthier life. Think of us as your healthcare home base.

Office Hours

Office Hours:
Mon, Tue, Fri: 8AM–5PM
Wed: 8AM–3:30PM
Thu: 8AM–4:15PM
Sat–Sun: Closed
Lab Hours:
Mon–Fri: 8AM–12PM, 1PM–4PM
Sat–Sun: Closed


10:00AM 60 min
11:00AM 25 min
11:45AM 60 min
10:00AM 60 min
See a provider
Book an appointment online today. Become a One Medical member for just $199/year.


1230 Columbia Street

Suite 100

San Diego, CA 92101




Get Directions


We are located on the corner of Columbia Street and B street. We are attached on the ground level of the 2 Columbia Place building, but we are not accessible from the lobby of the Columbia Place building because our entrance is on the exterior sidewalk. We are on the left of the parking garage entrance and the Mudbar Coffee stand (under the orange canopy).


Indoor parking garage attached at 2 Columbia Place; validation is offered at the front desk up to 30 mins for office visits and 15 mins for covid testing visits or labwork. Other options: metered street parking and two outdoor public parking lots on the corner of A St. and Columbia St.