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Downtown San Diego

Our Downtown San Diego office is located in the heart of the city, near Little Italy, the Gaslamp District, Broadway Pier, and Seaport Village.

Our whole patient experience is designed for real life — from same-day appointments that actually start on time to 24/7 video visits to compassionate providers who listen. We focus on building real relationships with patients and using technology to simplify every aspect of getting care. And we’re not just here for when you’re sick or injured. We can also help you meet physical and mental health goals, manage chronic illnesses, and live a happier, healthier life. Think of us as your healthcare home base.

Office Hours

Office Hours:
Mon-Fri 8am-4pm
(Closed 11/26-11/27, 12/25, & 1/1 in observance of the holidays)
Lab Hours:
M - F: 8am-12pm and 1pm-3pm
Flu shots available on walk-in basis


10:00AM 60 min
11:00AM 25 min
11:45AM 60 min
10:00AM 60 min
See a provider
Book an appointment online today. Become a One Medical member for just $199/year.


1230 Columbia Street

Suite 100

San Diego, CA 92101




Get Directions


We are located on the corner of Columbia Street and B street. We are attached on the ground level of the 2 Columbia Place building, but we are not accessible from the lobby of the Columbia Place building because our entrance is on the exterior sidewalk. We are on the left of the parking garage entrance and the Mudbar Coffee stand (under the orange canopy).


Parking garage attached at 2 Columbia Place ($2 each 15 minutes, $8 per hour; credit card only), metered street parking, two public parking lots on the corner of A St. and Columbia St.