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Downtown San Diego

Our Downtown San Diego office is located in the heart of the city, near Little Italy, the Gaslamp District, Broadway Pier, and Seaport Village.

Our whole patient experience is designed for real life — from same-day appointments that actually start on time to 24/7 video visits to compassionate providers who listen. We focus on building real relationships with patients and using technology to simplify every aspect of getting care. And we’re not just here for when you’re sick or injured. We can also help you meet physical and mental health goals, manage chronic illnesses, and live a happier, healthier life. Think of us as your healthcare home base.

Next Open House on Wednesday, August 14, 2019, 4:00pm - 6:00pm:

Come join us for an open house and meet our exceptional providers in our new San Diego Office. Learn about our philosophy of care and One Medical's unique approach to primary care. We’re not your typical doctor’s office and can't wait to show you the difference. All potential, new and/or existing members are welcome. Enjoy light bites and refreshments.

RSVP on ourEventbrite page

Future Open House Dates:

August 28, 2019 4:00pm - 6:00pm

September 4, 2019 4:00pm - 6:00pm


Office Hours:
Monday - Friday: 8am-6pm
Lab Hours:
Monday - Friday: 8am-12pm and 1pm-3pm


We are located on the corner of Columbia Street and B street. We are attached on the ground level of the 2 Columbia Place building, but we are not accessible from the lobby of the Columbia Place building because our entrance is on the exterior sidewalk. We are on the left of the parking garage entrance and the Mudbar Coffee stand (under the orange canopy).


Parking garage attached at 2 Columbia Place ($2 each 15 minutes, $8 per hour; credit card only), metered street parking, two public parking lots on the corner of A St. and Columbia St.


1230 Columbia Street

Suite 100

San Diego, CA 92101



10:00AM 60 min
11:00AM 25 min
11:45AM 60 min
10:00AM 60 min
See a provider
Book an appointment online today.
Become a One Medical member for just $199/year.