One Medical - Midtown 42nd Bryant Park
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Primary Care Doctor's Office in New York, NY Bryant Park

Our Bryant Park office offers exceptional primary care for adults of all ages, including seniors on Medicare. We’ve designed our member experience for real life — from same-day appointments that start on time to 24/7 video chat to compassionate providers who listen. We focus on building real relationships with patients and using technology to simplify every aspect of getting care. And we’re not just here for when you’re sick or injured. We can also help you meet physical and mental health goals, manage chronic illnesses, and live a happier, healthier life. Plus, you can expect improved coordination of specialty care through our affiliation with Mount Sinai Health System. Think of us as your home for healthcare.

Join One Medical

Interested in becoming a member or learning more about One Medical?

Membership benefits you’ll enjoy

  • Get 24/7 on-demand care nationwide via Video Chat or Treat Me Now at no extra cost
  • Send and receive secure messages with a provider
  • Easily access your health records and care plans
  • Request prescription refills and renewals
  • Book an in-person or remote visit in a state where we have offices

489 5th Avenue

3rd Floor

New York , NY 10017

Get Directions

Contact us:

Office Hours:

Mon–Fri: 8AM–6PM
Sat–Sun: Closed
RN Hours: Monday through Friday 9am-12pm & 1pm-4pm (ages 18+)

Lab Hours:

Mon–Wed: 8AM–6PM
Thu: 8AM–5PM
Fri: 9AM–2:30PM, 3PM–5PM
Sat–Sun: Closed


Public Transportation

Nearby Subway Stations
  • B, D, F, M, 7 to Bryant Park
  • 4, 5, 6 to Grand Central
  • 1, 2, 3 to Times Square
NYC MTA Home Page

Additional Information

Our Midtown - 42nd Street office is at 489 Fifth Avenue, across the street from Bryant Park and the New York Public Library. Our doctor's office is also directly next to Orvis Clothing Store.

Unfortunately, bikes are not allowed inside the building at this time.

No appointment needed if coming in during walk-in lab hours to fill a lab order that has already been ordered.

Our services

Think of us as your home for healthcare — your go-to for preventive care like physicals and screenings and your first stop when something feels off.

Frequently asked questions