One Medical - Midtown 42nd Bryant Park
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Midtown – 42nd St

Our Midtown - 42nd Street doctor's office is conveniently located in the heart of Midtown. We offer personalized primary care and can help with the everything from sinus infections and STD testing to digestive disorders and birth control counseling. We are not your typical doctor's office - from routine care to treatment of chronic conditions, our providers are committed to you and your health. We are in-network with most health insurance plans and offer straight-forward pricing for people without insurance. We're changing the way people think about seeing a doctor with same-day appointments and a modern approach.

Office Hours

Office Hours:
Mon, Tue, Thu, Fri: 8AM–6:30PM
Wed: 8AM–1PM, 2PM–6:30PM
Sat–Sun: Closed
Lab Hours:
Mon–Thu: 8AM–4PM
Fri: 8AM–11:45AM, 1PM–4PM
Sat–Sun: Closed
Drop in RN hours: No Hours 10/18-10/22 *Flu shots by appointment only


10:00AM 60 min
11:00AM 25 min
11:45AM 60 min
10:00AM 60 min
See a provider
Book an appointment online today. Become a One Medical member for just $199/year.


489 5th Avenue

3rd Floor

New York, NY 10017



Public Transportation

Nearby Subway Stations
  • B, D, F, M, 7 to Bryant Park
  • 4, 5, 6 to Grand Central
  • 1, 2, 3 to Times Square
NYC MTA Home Page

Additional Information

Our Midtown - 42nd Street office is at 489 Fifth Avenue, across the street from Bryant Park and the New York Public Library. Our doctor's office is also directly next to Orvis Clothing Store.

Unfortunately, bikes are not allowed inside the building at this time.

No appointment needed if coming in during walk-in lab hours to fill a lab order that has already been ordered.