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Testing and Prostate Cancer Screening: What You Need to Know

Jun 22, 2026 By Spencer Rizk, DNP
Men's health

Few screening tests generate as much confusion as the Prostate Specific Antigen or PSA test.

Over the years, recommendations have changed, headlines have conflicted, and many patients have been left wondering whether they should be screened for prostate cancer at all.

The answer is that it depends.

What is a PSA?

Prostate-specific antigen, is a protein produced by the prostate gland that can be measured through a simple blood test.

Higher PSA levels can sometimes indicate prostate cancer, but they can also be caused by benign prostate enlargement, inflammation, infection, recent ejaculation, cycling, or other non-cancerous conditions.

Because of this, PSA testing is no longer viewed as a simple "yes" or "no" decision.

Screening should be individualized

Most medical organizations now recommend shared decision-making, meaning patients and healthcare providers discuss the potential benefits and drawbacks together before deciding whether screening makes sense.

These conversations often begin between ages 45 and 55 depending on personal risk factors.

Individuals with a strong family history of prostate cancer, Black patients, and those with certain inherited genetic mutations may benefit from earlier discussions.

A quick note about testosterone and finasteride

This is especially important because many patients today are using testosterone replacement therapy or finasteride for hair loss.

Testosterone therapy may cause small PSA increases and often requires routine PSA monitoring as part of ongoing treatment.

Finasteride, on the other hand, typically lowers PSA values by roughly 50 percent. Because of this, healthcare providers often adjust PSA interpretation in patients taking finasteride to avoid underestimating risk.

Always let your provider know if you're taking either medication before PSA testing.

Not every prostate cancer needs treatment

One of the biggest misconceptions about prostate cancer is that every diagnosis requires immediate treatment.

In reality, many prostate cancers grow very slowly and may never cause symptoms or shorten a person's life. For some patients, active surveillance, which involves careful monitoring rather than immediate intervention, may be the most appropriate approach.

What can you do?

There is no guaranteed way to prevent prostate cancer, but maintaining a healthy weight, exercising regularly, avoiding tobacco, and eating a balanced diet support overall health and may help reduce risk.

The most important takeaway is this: prostate cancer screening is not one-size-fits-all.

Rather than relying on headlines, social media, or advice from friends, have a conversation with your healthcare provider about your personal risk factors, family history, and goals. The best screening decision is one that is informed, individualized, and made together.

Spencer Rizk, DNP, One Medical Provider
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